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Fc γ RIIB (CD32B)
rheumatoid arthritis and Hodgkin lymphoma
Acts as a regulator of cellular senescence and cellular ploidy by mediating phosphorylation of 'Ser-464' of LATS1
altering the sensitivity of target tissues to leptin actions and producing a state called leptin resistance in analogy to in sulin resistance
Polymorphisms of the FcγRIIIa gene associated with high or low affinity for Ig Fc have been described that could influence the efficacy of rituximab binding affinity
Alexa Fluor® 488 Mouse Anti-Human CD16a Antibody (S-564-39) Size:500T Fc γ RIIB (CD32B)Product Specification Host Mouse Antigen CD16a Synonyms Low affinity immunoglobulin gamma Fc region receptor III A; IgG Fc receptor III A; CD16 II; CD16a antigen; Fc gamma RIII alpha; Fc gamma RIII; FcRIII; FcRIIIa; FcgammaRIIIA; FcR 10; IgG Fc receptor III 2; FCGR3A; FCG3; FCGR3; IGFR3 Immunogen Synthetic Peptide Location Secreted, Cell membrane Accession P08637 Clone Number S 564 39 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity
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